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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • Sep 28th, 2014
    Someone from Mount Pleasant, MI signed.
  • Sep 28th, 2014
    Someone from Great Bend, KS writes:
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    Am currently taking the lupron injections and not happy with side effects mainly the bleeding and ankle knee legs and arms pain! Also my wrists hurt... I bleed horribly at random times and am so exhausted. My doctor claimed that this was the only option i had left... im due for my next injection november 4th and am dreading it I have gained so much weight since the shot and hormone replacement pills premarin and norethindrone
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  • Sep 28th, 2014
    Someone from Pleasant Lake, MI signed.
  • Sep 28th, 2014
    Someone from Lusby, MD writes:
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    I was given Lupron for 9 months and was told that the only side effects would by menopause and hot flashes. I told my GYN after 2 months that I was having joint pain in my hands and he dismissed it. 3 months after I was done with Lupron, my fingers and wrists hurt all the time and I also developed Colitis. Diarrhea every single day for 16 months straight. Sometimes I had it up to 12 times in a 24 hour period. The joint pain moved into my back. An MRI has shown arthritis in all of the facet joints in my Lumbar spine. I was 41 and my back never bothered me before. 3 years later, the arthritis has spread to both of my SI joints. So now I have terrible pain in both hips as a result. I have to have steroid injections in each joint on both sides. If I'm lucky I will have some pain relief for a couple of weeks. There is NO cure!!! I also developed Uveitis in both eyes. None of the Opthomologist that I have seen could tell me why someone so young should develop this disease. I had to have cataract surgery in both eyes at the age of 42!! This drug has stolen my life, my good health and time with my children. We have to make the pharmaceutical company STOP making this poison and also make them pay for sending us to an early grave!!
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  • Sep 28th, 2014
    Someone from Henderson, NV signed.
  • Sep 28th, 2014
    Someone from Saint Marys, GA signed.
  • Sep 28th, 2014
    Someone from Napa, CA writes:
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    These injections have turned my life upside down, in 5 years I have gone from a healthy active happy person to someone who is in pain all the time, terrible short term memory problems immune deficiency that has landed me in the hospital or ER almost every month, with so much going on my doctor has struggled to make sense of what is going on with me but take a look at all the women who have taken these injections and it's staggering how we all suffer from very similar problems and all since taking Lupron.
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  • Sep 27th, 2014
    Someone from Fort Lauderdale, FL writes:
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    There are no words to describe what this drug has done to my health. I do not recommand this drug!!!!!
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  • Sep 26th, 2014
    Someone from Bakersfield, CA signed.
  • Sep 26th, 2014
    Someone from Littleton, CO writes:
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    Took Lupron in 2001 and was so sick that I couldn't work had vomiting, weakness, bone pain, muscle spasm, muscle and joint pain, fatigue, low sex drive and today I still have everything except vomiting and the weakness comes and goes. The joint pain is just getting worse. I wish I had never taken this medication. I trusted the doctor now I don't trust any doctors I research as if I am the doctor and make decisions on the treatment options presented me very well informed. I prefer natural when I can.
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  • Sep 26th, 2014
    Someone from Pocono Summit, PA signed.
  • Sep 26th, 2014
    Someone from Champaign, IL signed.
  • Sep 26th, 2014
    Someone from Gering, NE writes:
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    Currently 23 received injection at age 19 I have suffered horrible side effects since including migraines, joint pain, especially hip and back pain ,hair loss(I have no eyebrows hair on my head,) fatigue(I nearly can get up in the morning it hurts because my babies need me)muscle pain, swollen hardened lymph nodes, weight loss(I weighed 198 before the injection now 114 and trying my best to gain) I now have a heart murmur,tachycardia so on so forth. My life is a struggle from day to day to get up in the mornings try n suck up the pain and start the day smiling for my babies when all I want to do is curl up in a ball and cry. Please please take this drug off the market n save the next group of women before its to late.
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  • Sep 25th, 2014
    Someone from Coats, NC writes:
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    Lupron took a vivacious woman and completely ruined her. Sadly, that woman is me. I had SEVERE memory problems, insomnia, anxiety, depression, body pain, fibromyalgia I am sure, migraines or at minimum a CONSTANT terrible headache, lack of energy, I stay fatigued, sex drive GONE... these are just the things I can think of off the top of my head. I took 2 shots (the 3 month kind) in 2007- that was to put me in short term menopause 6 months- lasted 9... but here it is near 8 years later, and the effects I listed are things I suffer with even now and am trying to come to grips with the fact they are most likely permanent. LUPRON RUINED MY LIFE! LUPRON TOOK MY LIFE... from me, my husband and my family.
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  • Sep 25th, 2014
    Someone from Pine Grove, CO writes:
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    I am 36 years old and have lost my life. I have been sick for four years. Everyday is a constant struggle. This drug is dangerous!
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  • Sep 25th, 2014
    Someone from Bakersfield, CA writes:
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    I have fybfoids in uterus. Due to a small stent in heart, oast surgery complications in 1995, and diabetes, I'm high risk for surgery! So after five Drs, one decided to do Depo Lupron shots. I ended up on it 8 straight months! Now I have rheumatoid arthritis amongst other issues! I. A mess! I feel the shots are most of the cause.I want to sue!!!!
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  • Sep 25th, 2014
    Someone from Greensboro, NC signed.
  • Sep 25th, 2014
    Someone from Topeka, KS signed.
  • Sep 24th, 2014
    Someone from Lakeside, CA signed.
  • Sep 24th, 2014
    Someone from Berkeley, CA writes:
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    My doctor told me no one at her hospital which is highland hospital in Oakland has ever experienced side effects like me. I have extreme joint pain, memory loss, fatigue where sometimes I fall. Dizziness, hotflashes and just over all pain with no pain management help at all. I being made to think i am crazy.
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  • Sep 24th, 2014
    Someone from El Cajon, CA writes:
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    This could explain a lot....
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  • Sep 24th, 2014
    Someone from Riverview, FL signed.
  • Sep 24th, 2014
    Someone from Riverview, FL writes:
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    I had 1 injection but have the symptoms of using for 3-6 months. Severe bone/joint/muscle pain. Osteopenia, peroneal nerve damage, Fibromalgia, migraines, miscarriages/infertility after the injection. The list goes on. I am in so much pain. I want not only a study but how about a diagnosis or syndrome that drs know that we are not drug addicts or hypochondriacs but that we were injured from a medication that was suppsed to hp us with fibroids/endometriosis. Because I still had a hysterectomy. I am 37 and had injection in 2006 (June) Know that pain scale drs say. That month was the worst pain I had ever been in. I Even had a seizure week 2. I refused the 2nd shot. I missed my daughter learning to walk because of this injection. i could barely move. I couldnt hold/lift her. And I still suffer.
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  • Sep 24th, 2014
    Someone from Wilmington, DE writes:
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    What a shame that health professionals continue to use this product... Risks are real.
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  • Sep 24th, 2014
    Someone from Wilmington, DE signed.
  • Sep 24th, 2014
    Someone from Canoga Park, CA signed.
  • Sep 24th, 2014
    Someone from Bismarck, ND writes:
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    Thank you all for sharing your stories. It brings tears to my eyes. I was diagnosed with endo 3 weeks ago and had surgery last week. My doctor has constantly been pressuring me to take these injections and says it's the only thing that will help. She said she doesn't support my decision for refusing it. I will be looking for a new doctor. Please take this drug off the market. So many people trust their doctors form of treatment in hopes to get rid of the pain. This drug should not be an option.
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  • Sep 23rd, 2014
    Someone from Redford, MI signed.
  • Sep 22nd, 2014
    Someone from White City, OR writes:
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    I've had the 3 month shot for 1 month. I've been extremely depressed, suicidal, wore a holter monitor because of anxiety and tachycardia and palpitations. I hate everything. This is worse than PMS. I want to die.
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  • Sep 22nd, 2014
    Someone from Seattle, WA signed.
  • Sep 22nd, 2014
    Someone from Broken Arrow, OK writes:
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    help us...at a minimum can we get some acknowledgement of these issues and research leading to suggestions to improve our quality of life?
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  • Sep 21st, 2014
    Someone from Crown Point, IN writes:
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    I suffer from memory issues, depression, pain and many other symptoms because of Lupron. This drug ruined my life!!!!!!!
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  • Sep 17th, 2014
    Someone from Farmington, WA signed.
  • Sep 17th, 2014
    Someone from Alton, IL writes:
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    I had this treatment in 2004 after having a laparoscopy to diagnose Endometriosis and I had relief for the first time in years but the side effects were awful and I feel like I still have side effects from this. after stopping treatment I immediately had my symptoms of endometriosis back. I have been going through a battery of tests for a few months now and they can find nothing they believe that the endometriosis has spread into my abdomen. I am going to request a hysterectomy and will also probably need another surgery to burn out the endometriosis. I will never do Lupron or anything similar to it again just not worth the pain it causes. I have been diagnosed with osteoarthritis in both knees (grade 4) and I early stages of osteoporosis. I also have horrible stomach problems.
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  • Sep 16th, 2014
    Someone from Wilkes Barre, PA writes:
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    After one shot,I was diagnosed with an auto immune disorder.The side effects are the worst!!and the Doctor did not tell me the risks!Angry,Sad and now i have to go get more testing done to see the damage it has done.
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  • Sep 15th, 2014
    Someone from Mount Vernon, NY signed.
  • Sep 15th, 2014
    Someone from Wilmington, NC signed.
  • Sep 12th, 2014
    Someone from Leetonia, OH writes:
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    I've taken lupron for 6i m yrs.ago let me tell u pure hell .....pure hell ....I still suffer to this day I never had any of of the symptoms before untill I took the lupron shot ....please get this drug off the market. I know all my symptoms are caused by that injection ....so ladies listen to your body thank you! by
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  • Sep 11th, 2014
    Someone from White Plains, NY signed.
  • Sep 11th, 2014
    Someone from Clearwater, FL signed.