Investigation into Lupron Side Effects (Leuprolide Acetate)

Long Term Side Effects of Lupron Depot (Leuprolide Acetate

The purpose of this petition is to warn others regarding the drug Lupron (Leupolide Acetate) mfg. by Takeda/Abbott Pharmaceuticals in the hope that further long-term safety studies are done before it disables or kills more women. This drug was originally marketed to treat prostate cancer patients but now is widely used for the treatment of endometriosis, infertility, fibroids/ovarian cysts and even precocious puberty.



Many women are continuing to suffer the side effects long after taking their last dose even though their doctor and the pharmaceutical company states that the side effects should go away within 3-6 months. Side effects include but are not limited to: hot flashes, memory loss, tachycardia, hematura, hypotension, dizziness, insomnia, anxiety, depression, Vitamin D deficiency, constant gnawing bone/joint pain, osteoarthritis, osteopenia, osteoporosis, fibromyalgia, degenerative disc disease, autoimmune diseases, blood disorders, cancer and many others including death and yet not one long term study has been conducted.



It is devastating to us that we agreed to take an FDA approved drug under the care of our physician whom we trusted only to find ourselves sicker than you could imagine ---- in pain and unable to get the proper treatment or even believed that Lupron caused our problems.



We hereby request that an investigation be undertaken into the short term and long term effects of Lupron on women. We further request that all outcomes and results of such trials be released and published so that both patients and doctors alike may have the benefit of all the information regarding this drug.




Take Action! First, Enter Your ZIP Code


Public Comments (5,043)
Nov 27th, 2018
Debra H. from Lisbon, NY writes:
Quotation mark icon
I was told to “cure” my Endo I just had to try this drug..this was in the 80’s..I went through hell..now I have terrible joint problems..memory loss..etc..I’m scared.. This isn’t right that 40 yrs later ..this poison is still being pumped into women of all ages..some testimonies from girls as young as 12..doctors of course are receiving monies.vacations..etc..to pump poison.. Please..enough..it’s time for this pharmaceutical company to tell the truth..and pull this poison out of Endometriosis verbiage..
Nov 7th, 2018
K.D. O. from New York, NY writes:
Quotation mark icon
I took two trial of Lupron in 2008 and I have horrible memory loss. It’s started while being treated and was told that it would get better after treatments. It’s still difficult to retain almost any new information and impossible to recall old memories. My vision problems started around the same time; prior to treatment I had 20/20 vision.
Nov 7th, 2018
K.D. O. from New York, NY writes:
Quotation mark icon
I took two trial of Lupron in 2008 and I have horrible memory loss. It’s started while being treated and was told that it would get better after treatments. It’s still difficult to retain almost any new information and impossible to recall old memories. My vision problems started around the same time; prior to treatment I had 20/20 vision.
Nov 7th, 2018
K.D. O. from New York, NY writes:
Quotation mark icon
I took two trial of Lupron in 2008 and I have horrible memory loss. It’s started while being treated and was told that it would get better after treatments. It’s still difficult to retain almost any new information and impossible to recall old memories. My vision problems started around the same time; prior to treatment I had 20/20 vision.
Nov 2nd, 2018
Sarah M. from Manitou Springs, CO writes:
Quotation mark icon
I was put on lupron to induce menopause in January of 2018 and received my last shot April 30th, 2018. since March I have had memory trouble, severe joint pain, numb hands to the elbows, stiff knees with severe pain when bending, anxiety attacks, and shoulder dislocation of both shoulders. It is now November and while I can now feel most of my fingers and bend the knees with slightly less pain all the other symptoms are still raging. Lupron took one debilitating problem away and replaced it with another. I truly feel Lupron was not necessary, the doctor had surgically confirmed endometriosis during a hysterectomy, and making me wait a year to go through this drug process he insisted was necessary to get the oopherectomy has taken a year away, with no telling when my symptoms will subside. This is a nasty, horrible drug!
Oct 25th, 2018
Melissa B. from San Diego, CA writes:
Quotation mark icon
I took Lupron quarterly shots in 2016 and 2017 . I had 6 quarterly shots. During my time on it, I had bone, joint and muscle pain. I had mind fog and could not focus. My memory could not retain information. I feel sick and depressed. My lab results were out of control. My glucose numbers were reaching 350. My vision worsened. My insides felt hot. My doctors told me this will go away once I stop the shots. I stopped and waited for it to detox out of my system. My last shot was November 2017. I still have the symptoms and I have more. Researching this drug I found that it is chemo and it damages your healthy cells. I found that thousands of people who took this are experiencing a regression in health. It seems to be deteriorating their mental and physical health. I am not the same. I’m still hoping that I will get myself back. This drug is toxic and poison.
Oct 18th, 2018
Someone from Kailua Kona, HI writes:
Quotation mark icon
At the age of 28 (2 year's ago) I was diagnosed with endometriosis and shortly after agreed to lupron injections. I only got the first shot, was thrown into an artificial menopause and felt as though I was slowly being poisoned. A whole******storm of nasty side effects came with it. Now fast forward to now, my left side (side I got the shot in) has sever nervous system damage, my speech is delayed, my motor skills are off, I'm extremely forgetful (thing's I've known for year's) dizziness every day, even my teeth are now going down the drain. The lower back pain is horrible,and my joints hurt all the time now. I'm only 30 year's old, I didn't know it was a chemo drug......
Oct 11th, 2018
Someone from Marengo, IL writes:
Quotation mark icon
After one shot I'm having horrible side affects which include nausea, lack of appetite, fatigue, insomnia, anxiety, pain in hips and back, extremely painful period, coughing, hot flashes and chills, brain fog amongst other things. I was not told prior to the injection that this was a chemo drug. I was told I would only feel hot flashes and moodiness. This drug is a lie!
Aug 17th, 2018
Someone from Gig Harbor, WA writes:
Quotation mark icon
This drug only added to my daughters problems. She suffers much from very real long term side effects including an increase of white brain matter in her brain, extremely bad migraines, auto immune issues and much more.
Apr 11th, 2018
Melody A. from Clarington, OH writes:
Quotation mark icon
Was found to have Endometriosis around age 19. Suffered with severe menstraul pain along with heavy bleeding. Caused lots of health issues. Had several diagnostic laparoscopic procedures. Nothing helped the pain that took over my life. I can tolorate pain to a point. Then my obgyn explained how Lupron Depot injections for 6 months were the next step. I was told only other choice would be a total Hystorectomy. I was young and wanted to option of having a third child. So I took those shots once a month every 28 days. Side effects yeah lots and the cost high. If I only knew before taking them, well I wouldn't of. About 4 years later had emergency hysterectomy. Lupron Depot had caused extreme headaches, numbness all over, blurred vision, so many health issues never had until after I started injections. Even my teeth were affected. I am 44 now live in pain daily. I am now undergoing diagnostic tests for a brain tumor. Please do something so others don't use Lupron Depot without understanding all the risks involved.

(c) Petition2Congress, all rights reserved. For web site support: email info@rallycongress.com or call (202) 600-8357