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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • Apr 3rd, 2010
    Someone from West Linn, OR writes:
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    Took 6 month shot 3 times -- the hot flashes make a guy nuts!
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  • Apr 2nd, 2010
    Someone from Houston, TX writes:
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    In 2000, I was given 6 Lupron shots for Endometriosis. Immediately I felt the side effects. Severe bone pain, headaches, bloating, weight gain (60 lb's in 6 months), hot flashes, exhaustion, suicidal depression, anxiety, etc. There are just too many to list. I stupidly continued the shots because my Doctor pushed them. After the shots, I had a Lap to check the Endometriosis and it had accelerated the growth of the tissue so much that I had to have a radical hysterectomy. My doctor blew off all my complaints and told me all side effects would go away. Well, it's 10 years later and I still have a lot of the symptoms along with Lupus, Diabetes and a host of other chronic ailments. My life was irreversibly damaged by this horrible drug as well as thousands of other women, men and sadly, now children. TAP Pharmaceuticals should be held accountable for all the lives they have ruined by selling this drug. Lupron is EVIL!
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  • Mar 30th, 2010
    Someone from Woodstock, GA writes:
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    on and off for 2 years of Lupron and 10 years later on & off knee pain.... Aching joints in legs and knees...
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  • Mar 30th, 2010
    Someone from Bronx, NY writes:
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    During the last month of my 90 day Lupron shot, I have been experiencing severe, constant headaches. I went to the emergency room to ease a blinding, icepick in head headache 3 days ago. When I discussed that I had never before suffered from chronic, excruciating headaches for weeks on end, the doctor suggested it wasn't a side effect from Lupron, but an internal problem with my body. Considering I haven't ever experienced symptomatology like this before, I was highly offended by this doctor's remarks. They referred me to a pain management doctor and washed their hands of the situation. I expected the menopausal symptoms, but not severe intense migranes. Although the 90 days will be up in one week, I am very concerned about the headaches continuing indefinitely.
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  • Mar 29th, 2010
    Someone from Seymour, TN writes:
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    Caused severe hypertension which in turn caused permanent loss of kidney function. Arthritis in hands, feet, hip, and neck. So bad in neck that I have headaches 24/7. Vision problems come and go. I am now on 3 blood pressure medicines. Extreme fatigue. Memory loss.
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  • Mar 27th, 2010
    Someone from Ithaca, NY writes:
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    I have been on Lupron for three months. I have been suffering from anxiety,high blood pressure,swelling of the legs and arms, aches and pains in my muscels and joints. Been to a cardiologist and had my heart ruled out, had my leg checked for a blood clot and have missed a ton of work. This drug has been a nightmare for me. The fibroid has shrunk but these problems are much more painful then the fibroid was. I would have been better off to have the fibroid taken out. But this was not the advise of my doctor. And now look where I am. THIS DRUG NEEDS TO BE OUTLAWED AND DOCTORS SHOULD DO SURGERY AND NOT BE SO LAZY and so easy to give this drug out.>
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  • Mar 25th, 2010
    Someone from Pahrump, NV writes:
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    Quadruple bypass 2 months after taking Lupron
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  • Mar 24th, 2010
    Someone from Hickory, NC signed.
  • Mar 22nd, 2010
    Someone from Morehead, KY writes:
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    I took this medicine in March 2005 through April 2006. I have had long term side effects, many that I am still dealing with. Migraines, memory loss, painful female organs, difficulty urinating, constipation, anxiety, depression, weight gain, sinus problems, fatigue. Yet the doctors only warn you that you will go through menopause and will have hot flashes. 5 years later I thought these would go away. People should definitely be warned when they take this of all possible side effects and how they won't won't go away.
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  • Mar 21st, 2010
    Someone from Lincoln, DE signed.
  • Mar 19th, 2010
    Someone from Hoboken, NJ writes:
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    Why isn't the FDA doing anything about this nightmare drug????? Why are doctors pushing it? Why do insurance companies cover it when it just leads to huge medical costs down the road??? How many women's lives have to be ruined before this is stopped??? I took only ONE shot of Lupron and still haven't recovered! It's Russian roulette for anyone to try this drug.
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  • Mar 19th, 2010
    Someone from Hoboken, NJ writes:
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    Why isn't the FDA doing anything about this nightmare drug????? Why are doctors pushing it? Why do insurance companies cover it when it just leads to huge medical costs down the road??? How many women's lives have to be ruined before this is stopped??? I took only ONE shot of Lupron and still haven't recovered!
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  • Mar 19th, 2010
    Someone from Hoboken, NJ writes:
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    Why isn't the FDA doing anything about this nightmare drug????? Why are doctors pushing it? Why do insurance companies cover it when it just leads to huge medical costs down the road??? How many women's lives have to be ruined before this is stopped???
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  • Mar 16th, 2010
    Someone from Sun Prairie, WI signed.
  • Mar 15th, 2010
    Someone signed.
  • Mar 11th, 2010
    Someone from Fenton, MI signed.
  • Mar 10th, 2010
    Someone from Littlestown, PA signed.
  • Mar 10th, 2010
    Someone from Littlestown, PA writes:
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    I was diagnosed with endometrosis 3 years ago, my Dr did the surgery and said I was at Stage 5. I had spent years having pain and other doctors saying nothing was wrong. After the surgery we started Lupron, took it for a year, no problems. Fast forward 3 years I have horrible pain again, muliply cyst, and when they tried to do the surgery I had an allergic reaction and my throat closed. Surgery was cancelled my parents were told how lucky I was to have been there when I had my reaction. Thing is I have had surgery before never had a reaction. Dr suggest Lupron, I had already been out of work because of the pain for 2 wks. I said ok. That night, I woke up with the worst headache of my life, started vomiting, sweating, it was horrible. My fiance rushed me to the hospital they said I was having a reaction to the Lupron. For 5 days I had this headache, and cramps. The headache is gone but it's been 20 days I still have cramps. I have noticed how depressed I have been lately and I wonder that bubbly woman I was disappeared after I took the shot the first time. I am 33yrs old and getting married in Oct, 2010 we want children. I am afraid to take the shot again. Can't congress help us in anyway.
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  • Mar 8th, 2010
    Someone from West Springfield, MA signed.
  • Mar 8th, 2010
    Someone from Millbury, MA signed.
  • Mar 8th, 2010
    Someone from Chicopee, MA signed.
  • Mar 8th, 2010
    Someone from Feeding Hills, MA signed.
  • Mar 7th, 2010
    Someone from West Springfield, MA signed.
  • Mar 7th, 2010
    Someone from Belchertown, MA signed.
  • Mar 7th, 2010
    Someone from West Springfield, MA signed.
  • Mar 7th, 2010
    Someone from New Castle, DE writes:
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    I've signed this before, and I, like the others are still suffering, but no longer in silence. It is the groups and support of my family, and the lupron family that have helped me through this, while the Drs bury their heads in the sand. My PCP said one time that lupron caused all the things wrong with me, but if you ask him today, in a legal setting, I'm sure he, like all the other Drs will do a complete 180. Drs don't like to go against other Drs. What gets me is that when Lupron was commiting ins fraud by giving free samples and the Drs were billing insurance companies, and getting lavish trips to get us to take their poison, it didn't take long for the government and legal people to step in then. I would love to see all the people that are ignoring us, in the FDA, the DRs that are saying it's safe to have these shots, and anyone that works at companies (the higher ups that make the decisions), to be the guinea pigs, let them take the poison. While each month my health gets worse and worse, I'd love to see how they would handle it, and I also would love to know if they would give this poison to their friends and family. I wonder what is said around the water cooler when one of them brings up that their Dr says they need to get lupron shots. I would bet any amt of money that they would move heaven and earth to convince that person NOT to get involved with Lupron.
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  • Mar 6th, 2010
    Someone from Fountain Valley, CA writes:
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    This drug Is the cause of my chronic pain syndrome aka fibromyoalgia. Before my first injection I did not have these problems.I was 21 that was in 1995! I have suffered daily since my treatment with lupron! I wish i was told that this was all possible side effect I would have NEVER had it as part of mt endometerosis, ovarian cyst treatment! Please remove it from the market! It has caused me nothing but more pain and problems it was no help!!! I so far have sufffered memory loss, tachycardia, hematura,dizziness, insomnia, some anxiety, some depression, Diagnosed Vitamin D deficiency, constant gnawing bone/joint pain, osteopenia, osteoporosis, diagnosed fibromyalgia,diagnosed degenerative disc disease, autoimmune diseases!! This drug is toxic and they do not inform you that these things can happen just that it will stope your mensus!
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  • Mar 5th, 2010
    Someone from Forked River, NJ writes:
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    THIS DRUG ABSOLUTELY SHOULD NOT BE APPROVED BY THE FDA....MANY,MANY LIVES HAVE BEEN DESTROYED BY LUPRON!! HOW MANY PEOPLE HAVE TO BECOME TOTALLY DISABLED OR EVEN DIE FROM THIS DRUG BEFORE SOMETHING IS DONE! THIS IS AN ABSOLUTE DISGRACE AND THE FDA SHOULD BE ASHAMED OF THEMSELVES FOR NOT REMOVING IT BY NOW!
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  • Mar 5th, 2010
    Someone from Jacksonville, AR signed.
  • Mar 5th, 2010
    Someone from Mildred, PA writes:
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    I almost died from endometriosis now I have permanant damage from that drug, because dr's dont often do more than just give it all that I am the 1 in 10 with the disease, does nobody understand my symptoms got worse I had a fullhysterectomy at 35 and now I shake stumble rashes possible for other auto immune diseases not to mention the mentally incapablities by the way used to be a english major, I becamebipolar depressed, anxiety came back full on ptsd all of it then some amplified.
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  • Mar 4th, 2010
    Someone from Fair Lawn, NJ writes:
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    My 12 year old has been on it for 8 months and I just took her off. She is cranky all the time, pale, vit. d deficient, complains of deep muscular and bone ache, diarrea and dizziness since being on it. I am very nervous of what the future holds for her.
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  • Mar 4th, 2010
    Someone from Cedar Falls, IA writes:
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    Lupron has changed my life dramatically. After nearly a decade of no complex PTSD symptoms, they returned full force after Lupron shots along with mood changes. It's been a year and a half, and I still can't get back to where I was pre-Lupron,
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  • Mar 4th, 2010
    Someone from Saint George, UT signed.
  • Mar 4th, 2010
    Someone from New York, NY writes:
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    I was getting ready to get tha lupron injection. I decided to do some research on this drug and due to all the side effects, I refused.
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  • Mar 4th, 2010
    Someone from Radford, VA signed.
  • Mar 2nd, 2010
    Someone from Jessup, MD signed.
  • Mar 2nd, 2010
    Someone from Bethlehem, PA signed.
  • Mar 2nd, 2010
    Someone from Slatington, PA signed.
  • Mar 2nd, 2010
    Someone from Huntersville, NC signed.
  • Mar 2nd, 2010
    Someone from Phillipsburg, NJ writes:
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    It is imperative that these drugs have intensive and continued studies to verify the safety and to identify potential side effects (remember thalidomide?)
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