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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • May 20th, 2015
    Someone from Hillsboro, OR writes:
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    I have never been the same since these injection
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  • May 20th, 2015
    Someone from Hendersonville, NC writes:
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    I was given just 1 shot out of 2 of Lupron 6 1/2 years ago to see if I did have endometriosis and if I needed to have a hysterectomy as I was young. About 6-8 hours after having the injection, I began to have headaches & I now have them everyday 24/7 with no relief. My body hurts, muscle weakness, muscle spasms, bone loss, muscle pain, bone pain...yeah everything. Saw drs at the Mayo Clinic in MN & was told I would be this way for the rest of my life as the injection did something to my nervous system. All before the age of 35.
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  • May 20th, 2015
    Someone from Wellington, KS signed.
  • May 19th, 2015
    Someone from Reno, NV writes:
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    Lupron gave me everlasting joint pain & insomnia that has negatively impacted my life for the last 2 years.. Get it off the market!
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  • May 19th, 2015
    Someone from Stroudsburg, PA signed.
  • May 17th, 2015
    Someone from Placentia, CA signed.
  • May 17th, 2015
    Someone from Philadelphia, PA writes:
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    Lupron has destroyed my life as I once knew it. I'm in pain throughout my entire body. Nerve, bone and joint pain with muscle spasms. My entire body burns as if someone is rubbing hot coals over my legs, arms and back. This is just some of side effects I must live with, not to mention servere back pain. I had none of these problems until I was given Lupron. My life is never going to be the same, all because some pharmaceutical company wants to make billions a year.
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  • May 16th, 2015
    Someone from Paso Robles, CA writes:
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    I have had 4 lupron injections. Horrible hot flashes, weight gain, headaches, skin hurts, joints hurt,back hurts,fatigue, frequent urination and now severe swelling of legs and feet with pain. This drug is horrible. After reading all of the posts it has me extremely worried.
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  • May 16th, 2015
    Someone from Bellevue, WA writes:
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    I was given a Lupron injection about 6 weeks ago for Endometriosis after surgery was not sufficient to control my constant pain. Since getting the shot (which did not reduce the Endometriosis pain, but actually made it worse), I have had constant headaches, hot flashes, night sweats, memory problems, mood swings, heart palpitations, severe anxiety, and have just started getting serious hip pain and burning in my muscles. I was not aware this was a chemotherapy drug or that it worked on your pituitary gland and had the potential to irreversibly impact your endocrine system. This drug is very dangerous!
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  • May 16th, 2015
    Someone from Elizabeth, NJ signed.
  • May 15th, 2015
    Someone from Concord, NC writes:
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    I was supposed to have 6 Lupron injections, but I only made it through 3. The side effects are still lingering. I have suffered headaches, nausea, joint paint, extreme fatigue amongst other issues as well. Lupron has severe side effects and it is time for it to be investigated.
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  • May 14th, 2015
    Someone from Dublin, GA signed.
  • May 14th, 2015
    Someone from Dublin, GA signed.
  • May 14th, 2015
    Someone from Rio Rancho, NM signed.
  • May 14th, 2015
    Someone from Wood Ridge, NJ signed.
  • May 13th, 2015
    Someone from Rio Rancho, NM signed.
  • May 12th, 2015
    Someone from Oakland, CA signed.
  • May 12th, 2015
    Someone from Oakland, CA signed.
  • May 12th, 2015
    Someone from Montross, VA signed.
  • May 12th, 2015
    Someone from La Crosse, WI signed.
  • May 11th, 2015
    Someone from Buffalo, NY writes:
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    I was administered two shots of lupron a month apart, to help conceive a child. My doctor believed I had endometriosis, and this would allow the lining of my uterus to grow back normally. I was in agony and tried to refuse the second shot. My obgyn said to do the second shot increase my chances of pregnancy. I did conceive our son a few months after stopping lupron, but have since had extreme joint and back pain. Recently I was told, at age 34, that I am in a Peri menopausal state, ten years before I should be. I have not been without pain since the bone pain I experienced during my lupron shots. I agree this drug needs to be furthered studied. Now there is talk of fibromialga as the reason for my pain. In pursuing a second pregnancy, I will go without another child before I resort to lupron. Awful!!!
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  • May 11th, 2015
    Someone from Orangeville, PA writes:
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    Let's see... I attempted suicide 3 times, I already had PTSD and Fibromyalgia and it has only gotten worse. Its almost like I'm Jekyll & Hyde. This is getting ready to end my 3rd 3 mo shot and I AM NOT going back on. I am ripping inside, where I had a seroma from August scraping of Endometriosis and it is ripping btwn Epidermis & Facia like a tunnel on my abdomen. I scream the pain is so bad. With each weakining of my abdominal wall, the fibers are just coming apart. Dr takes no responsibility & when I do go through withdrawal, I have to be observed in a psych hospital. I don't even realize what's going on. I just become self destructive and that's not good if we have IVF. I need to be completely detoxed of everything. If I had known that I would have problems walking, body aches & major pain, bowel issues, etc... I'd have asked for something different. Even w/ add back of Norethindrone & Premarin, it makes no difference. My husband liked me on Clomid a lot better. I'm driving him to drink. That's how bad it is.
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  • May 10th, 2015
    Someone from Pocahontas, AR signed.
  • May 9th, 2015
    Someone from Onalaska, WI writes:
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    This drug ruined my life
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  • May 8th, 2015
    Someone from Nome, AK signed.
  • May 8th, 2015
    Someone from Englewood, CO signed.
  • May 8th, 2015
    Someone from Barberton, OH writes:
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    I have taken lupron for a total of about 4 months! My body has completely changed over the last two years and I was puzzled as to why ....until someone brought the side effects of lupron to my attention! This drug is ruining people's lives. Something NEEDS to be done about this. I can only hope and pray these side effects don't last forever.
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  • May 7th, 2015
    Someone from Newport News, VA signed.
  • May 7th, 2015
    Someone from Coventry, CT signed.
  • May 7th, 2015
    Someone from Chaplin, CT signed.
  • May 7th, 2015
    Someone from Coventry, CT writes:
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    I would like to know how many Doctors are out there that gave this drug to their daughter? Probably none!!!! Its an evil drug. These women need a cure, not more debilitating problems. Please help them by signing this petition.
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  • May 7th, 2015
    Someone from Chaplin, CT signed.
  • May 7th, 2015
    Someone from Litchfield, IL writes:
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    I was given this drug under the name of "eligard" after my prostrate was removed May 2011. I was told the worst side effect will "possibly" be hot flashes. I took eligard even though my PSA was zero as a precaution. My PSA remained at zero for one full year and decided to stop the eligard. My PSA remained at zero without the eligard for 1 1/2 years. After this time my PSA went from .01 to .2. My Dr. Urged me to resume the eligard and that is when all hell broke loose. I started having joint pain, burning legs and feet along with mood swings, crying, constaption, muscle loss, anxiety stomach problems and the list goes on. This "Medication" must be looked at very carefully to determine if it must be removed from the market. One reason it it is still on the market is MONEY! Eligard for me was over $2500.00 per dose.
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  • May 7th, 2015
    Someone from Litchfield, IL writes:
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    I was given this drug under the name of "eligard" after my prostrate was removed May 2011. I was told the worst side effect will "possibly" be hot flashes. I took eligard even though my PSA was zero as a precaution. My PSA remained at zero for one full year and decided to stop the eligard. My PSA remained at zero without the eligard for 1 1/2 years. After this time my PSA went from .01 to .2. My Dr. Urged me to resume the eligard and that is when all hell broke loose. I started having joint pain, burning legs and feet along with mood swings, crying, constaption, muscle loss, anxiety stomach problems and the list goes on. This "Medication" must be looked at very carefully to determine if it must be removed from the market. One reason it it is still on the market is MONEY! Eligard for me was over $2500.00 per dose.
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  • May 6th, 2015
    Someone from Branson, MO writes:
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    I was administered this "treatment" when I was 16 & 17 years old. Fifteen years later I am STILL experiencing the debilitating side effects of this drug. It has caused me more sleepless tearfilled nights and bedridden days than I could ever count. Please stop this medication from taking more life from women and young girls.
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  • May 6th, 2015
    Someone from Ferrisburgh, VT writes:
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    The Lupron shot was given to me for severe PMDD. In the beginning it worked great but after the third shot (about 9 months later) I started having severe pain in my back, shoulders, spine and bones. It feels like "fire" in my body and sharp pain. I was never told of the possible side effects. I was already suffering from fybromialgia but this pain is way worst than the joint pain I was used to dealing with. Please, do not use Lupron, this drug is toxic. Now I feel like doing simple chores is very demanding because of this new pain.
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  • May 5th, 2015
    Someone from Wildwood, NJ signed.
  • May 4th, 2015
    Someone from Almond, NC signed.
  • May 4th, 2015
    Someone from Columbus, GA writes:
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    I was injected with the shot unwillingly and unknowing of the symptoms after emergency surgery from my endometriosis spreding to vital organs. I have experienced all the side effects that were not even explained to me, even the "rare" effects. This has ruined my quality of life, I am in constant pain and tired amongst many other things too long to list! This product (poison) needs to be taken down never to show it's ugly face again! Action needs to happen NOW to save someone the trials and tribulations this comes with! I also had no idea that this drug is also used as chemotherapy! I feel like my life was played with and I lost without even having a say I was just injected and told I needed it when asking what it was. I have more to say on this matter but this would literally take all day! Legal cases have been made since the 90's and no one has done anything since 2011 for some reason! Companies should not be more important that people's lives!!
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  • May 2nd, 2015
    Someone from Cleveland, OH writes:
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    I took the shots for six months in 1994 and 1990. It was for stage IV endometriosis- since then, I have had severe joint pain, fibromyalgia, bladder cancer, hashimoto syndrome- to name a few! I am convinced it is due to this drug.
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