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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • Dec 27th, 2012
    Someone from Chaparral, NM writes:
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    Please stop this drug! A couple of years ago I was diagnosed with endometriosis. I had a laproscopic surgery to remove grrowths and cauterize damaged spots. I was then, by a well-respected doctor, issued 2 consecutive 3-month shots. Military insurance, about 5 months into my treatment, switched me to an on-base military hospital to continue my care. A young doctor, whom I no longer trust, then convinced me that the best bet would be to take 2 more shots. This was a total of four consectutive shots, which I agrued, but eventually gave in to. It helped temporarily, but the side effects mostly hit after use. My teeth are rapidly decaying, even though I previously had almost perfect ones. I have been having pain in my hips, but the doctors either don't care or don't believe me. I'm only 25 years old now, and feel about 60. Haven't got my period back. Hot flashes haven't gone away. I have been off the shot for 3 months. Doctors are somehow convinced that this drug cannot cause permanent damage if you use the "add back therapy" consisting of estrogen and calcium, but they are clearly wrong. Save lives, stop this poison.
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  • Dec 24th, 2012
    Someone from Woodbridge, VA writes:
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    I took Lupron depot 45 (last 6 months) after external radiation treatment for prostate cancer. Three days after Lupron injections I have had joint pains that do not stop. Literature talks to 2% having this effect but can not find any warning as to the severity of the pain. I am hoping that after 6 months the shot will wear off and the pain decrease or cease. It is now past the 6 months point and no change yet. I would be interested in knowing if there is some financial benefit to doctors prescribing this stuff and adverse research withheld from the FDA and physicians.
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  • Dec 24th, 2012
    Someone from Perrysburg, OH writes:
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    I have had years of joint pain after taking the lupron shot.
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  • Dec 20th, 2012
    Someone from Glen Ridge, NJ signed.
  • Dec 19th, 2012
    Someone from Salt Lake City, UT writes:
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    So glad I did some research, decided not to take the shots, thanks to all you who have commented and I pray for relief for your symptoms from the poison.
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  • Dec 19th, 2012
    Someone from Las Vegas, NV signed.
  • Dec 17th, 2012
    Someone from Westland, MI signed.
  • Dec 17th, 2012
    Someone from West Yarmouth, MA writes:
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    Ive been on lupron for two months ive have problems with my bones ,im so tired.I just dont feel like doing anything the doctors think this drug so good why dont they get it.i there too many side effects i cant even type without hurting i have multiple health problems.I just cant win i dont want anymore shot i have four more
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  • Dec 14th, 2012
    Someone from Sharon, PA signed.
  • Dec 13th, 2012
    Someone from Madison, IN writes:
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    Had pain in my arms two days after taking this. Keeps getting wrose so called my DR. and I quote this was not found in the test study... Then all of use taking this posion must be crazy? wounder why.. some one needs to help us.
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  • Dec 12th, 2012
    Someone from Kingston, NH writes:
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    OMG, I gave my daughter approx 48 shots of lupron for precocious puberty for 4 years. I took her off of it at 9years old after watching her gain over 50lbs in a year and half!! Shame on the drug co. and my daughters doctors!! She now has severe bone pain, Polycystic Ovary, fibromyalgia,memory loss, horrific headaches, night sweats,numbness 7 tingling throughout her body, heart palpitations and chest pain. it seems like every week a NEW symptom arises for my daughter!! This is truly a travesty that has CONTROLLED my 13year olds life!!Shame, Shame, Shame!!
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  • Dec 12th, 2012
    Someone from Circle Pines, MN signed.
  • Dec 11th, 2012
    Someone from New London, NH writes:
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    My daughter had precocious puberty and had monthly injections of Lupron for 5 years! She has had all of these symptoms and everyone still says it's not from the Lupron injections. Take this off the market at least until there are more sufficient tests done. It's been 6 years since her last dose and she is still suffering the side effects.
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  • Dec 11th, 2012
    Someone from Oaklyn, NJ writes:
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    I was told the only side effects were mood swings, hot flashes, and headaches. 3 months off this poison I now itch constantly, have frequent urination, liver damage, bladder complications, and abdominal pain no one can explain. TAKE THIS OFF THE MARKET NOW!!!!
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  • Dec 11th, 2012
    Someone from Wilmington, NC writes:
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    took this poison almost 20 yrs ago over a 9 month period of time & have never been the same since. this med needs to come off the market ASAP!!
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  • Dec 9th, 2012
    Someone from Fontana, CA signed.
  • Dec 9th, 2012
    Someone from Fontana, CA signed.
  • Dec 7th, 2012
    Someone from Florence, SC signed.
  • Dec 6th, 2012
    Someone from Sunnyside, WA writes:
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    Memory loss is horrific!
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  • Dec 6th, 2012
    Someone from Church Hill, TN signed.
  • Dec 5th, 2012
    Someone from Lancaster, OH signed.
  • Dec 5th, 2012
    Someone from Evanston, IL signed.
  • Dec 4th, 2012
    Someone from Lancaster, OH writes:
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    I was not warned of any side effects. I trusted my doctor and took the shots. It was not until I started experiencing side effects that I looked it up and found out how bad it was. I feel deceived!
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  • Dec 4th, 2012
    Someone from Los Angeles, CA writes:
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    My Doctor played God with my life and I have never been the same since. It's approximately 8 years and drowning.
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  • Dec 4th, 2012
    Someone from Cleveland, OH writes:
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    I receied lupron three years ago to treat endo...it did not only not treat it , it caused a domino effect of health issues. Before this shot i was rather healthy other than the endo, now i have chronic pain in every bone, joint, and muscle in my body.. I cant sleep and half the time can barely walk. I have problems concentrating and cant remember anything. I have been diagnosed with fybromyalgia, thyroid disease vertigo,and syncope since the injection.( all of which are side effects) This shot sucks, and I will probably be crippled before long. I am so mad that nothing is being done to prevent this from happening to other people.
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  • Dec 4th, 2012
    Someone from Salt Lake City, UT signed.
  • Dec 3rd, 2012
    Someone from Fredericksburg, VA signed.
  • Dec 3rd, 2012
    Someone from Spotsylvania, VA signed.
  • Dec 3rd, 2012
    Someone from Fredericksburg, VA writes:
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    Take it off the market...TAKE LUPRON OFF THE MARKET!!!! its effecting others in a bad way take it off and stop hurting peope
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  • Dec 1st, 2012
    Someone from San Pedro, CA writes:
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    The other night - I cried so hard after reading story after story of people severely suffering and/or dying (has died) as a large result of Lupron. I threw my snot rags at the mirror, disgusted at my faces - seeing the two of me again for the past 7 months. With each shot, I was told that "double vision" is not a side effect. It is not listed in any literature. Yet, after each shot, my vision progressed immediately for the worst, as well as ringing in the ears, headaches, fatigue, etc. My neuro-ophthalmologist said that I should have Lupron investigated. I never felt right about taking Lupron: I was talked into it by my GYN (as Tamoxifen would cause me more hemorrhaging) - It became part of my breast cancer protocol. After one full year on Lupron, my oncologist has finally stopped Lupron to see if I improve. His biggest concern with me has always been "cancer" spreading (I'm BRCA2+, cancer began growing shortly after exposed to the toxic cloud on 9/11). Recently, I began taking methyl B12 shots ... doing chelation therapy and other alternative treatments advised by my internist - in hopes to repair my entire system. He's also treated me for Lyme disease in the past. At first, I really thought that all these symptoms were Lyme-related, until tests proved something way deeper... What's "really" in these shots?... I cancelled my wedding a second time around, put my career on hold to become a full-time patient. Let me tell you, it's hard work! I'm not here to give some sad story... I'm here because people come over profit. I have two uncles on Lupron. One's leg is swollen so bad (edema - 2 years on Lupron), and the other can't walk anymore (5+ years on Lupron), bedridden. But, I'll walk all the way to Washington, DC, if I must, for all those whose blood has been tainted... For all the bloodshed and heartaches Lupron and the people who profit by it have caused...
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  • Nov 30th, 2012
    Someone from Hayward, CA writes:
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    I had several Lupron injections between 2008-2009. The pelvic and leg pain I endured with each injection was horrific but was told it was only temporary. I refused to have a 4th injection due to to discomfort. Now I constantly suffer from joint/ bone pain, insomnia, unexplained excessive weight gain, fatigue, depression and not to mention, memory loss. I wish that someone had taken a moment to tell me about the side effects before my first injection and I probably would have refused and just lived with the other discomfort. No one should have to live in constant pain just so someone else can make trillions of dollars. Why doesn't the FDA care? Lupron has made my life miserable
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  • Nov 28th, 2012
    Someone from New York, NY writes:
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    I can't even use my real name here because my injuries are so personal. I took Lupron ONCE and it destroyed my entire abdominal wall, leaving me with permanent severe abdominal distention that top surgeons told me couldn't be fixed. Even the drug maker admits Lupron causes hernias - see the Physicians Desk Reference. Although I've never weighed over 100 pounds, I had to have two abdominoplasties - which aren't covered by insurance - to reconstruct my entire abdominal wall. The surgeries were major - the second lasting 4.5 hours and requiring a graft of my own dermis - and helpful but not entirely successful. I have 23 inches of scars and approx. $50K in medical bills. This is from ONE 3.75mg shot of Lupron. All the doctors who prescribe Lupron to healthy young women are irresponsible, lazy, or corrupt. The drug received FDA approval based on falsified data and the drug maker has paid over $1 billion in fines for illegal marketing. Yet it continues. The FDA is corrupt.
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  • Nov 28th, 2012
    Someone from New York, NY writes:
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    I can't even use my real name here because my injuries are so personal. I took Lupron ONCE and it destroyed my entire abdominal wall, leaving me with permanent severe abdominal distention that top surgeons told me couldn't be fixed. Even the drug maker admits Lupron causes hernias - see the Physicians Desk Reference. Although I've never weighed over 100 pounds, I had to have two abdominoplasties - which aren't covered by insurance - to reconstruct my entire abdominal wall. The surgeries were major - the second lasting 4.5 hours and requiring a graft of my own dermis - and helpful but not entirely successful. I have 23 inches of scars and approx. $50K in medical bills. This is from ONE 3.75mg shot of Lupron. All the doctors who prescribe Lupron to healthy young women are irresponsible, lazy, or corrupt. The drug received FDA approval based on falsified data and the drug maker has paid over $1 billion in fines for illegal marketing. Yet it continues. The FDA is corrupt.
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  • Nov 27th, 2012
    Someone from Glenwood City, WI writes:
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    Lupron permanently and severely disabled my best friend, whom I have also lived with for the past decade. She has a refractory headache that never relieves, and that no medication has been able to alleviate. Her life is hell on earth because of the drug Lupron, and I am enraged that any pharmaceutical company is allowed to disable and maim human beings this way. LUPRON IS *NOT* A MEDICATION, IT IS A LETHAL, *INHUMANELY* LETHAL POISON.
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  • Nov 27th, 2012
    Someone from San Francisco, CA signed.
  • Nov 27th, 2012
    Someone from San Francisco, CA signed.
  • Nov 27th, 2012
    Someone from Douglas, GA writes:
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    Any drug that has side effects of 3 to 6 months has to be defective. TAKE LUPRON OFF THE MARKET!!!!
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  • Nov 26th, 2012
    Someone from Fort Lauderdale, FL writes:
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    My Dad is in bad shape from this screwed up drug. His Doctor won't even acknowledge the major side affects. Our Government sucks!!
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  • Nov 26th, 2012
    Someone from Pittsboro, NC signed.
  • Nov 26th, 2012
    Someone from Methuen, MA writes:
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    this drug needs to be taken off of the market. it is horrible that both pharma and gov't have done nothing about it while thousands of people are suffering terrible side effects.
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