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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • Oct 10th, 2013
    Someone from Camillus, NY signed.
  • Oct 10th, 2013
    Someone from Berthoud, CO writes:
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    My doctor recommended injections to stop fibroid bleeding. I had 3 injections total. I thought I was going to die after the third injection. I have never felt worse in my life and I have gone through a horrendous surgery on my spine, and that didn't even compare. My doctor eventually told me that I had developed fibromyalgia -- and that it was a side effect from the Lupron and could possibly stay with me even after the Lupron eventually left my body. My blood pressure skyrocketed so my doctor then prescribed blood pressure medication, which only made me worse. Finally after going off all medications, my body returned to a more normal state. I continue to have some pain, but nothing like what I was enduring while the Lupron was still in my system. I truly felt like I had been poisoned and was slowly dying. It was horrifying! This drug needs to be removed from the market. It should never be used on anything living. Please destroy it!
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  • Oct 9th, 2013
    Someone from Brooklyn, MD signed.
  • Oct 9th, 2013
    Someone from Katy, TX writes:
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    This is the most horrible of drugs, and have long hated it...my side affects are pretty classified: as "ALL OF THE ABOVE" plus some.
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  • Oct 9th, 2013
    Someone from Cleburne, TX signed.
  • Oct 9th, 2013
    Someone from Indianapolis, IN signed.
  • Oct 9th, 2013
    Someone from Corvallis, OR signed.
  • Oct 8th, 2013
    Someone from Puyallup, WA signed.
  • Oct 7th, 2013
    Someone from Kissimmee, FL writes:
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    1 shot that has changed my life forever, divorce, so many health issues for a person who did Crossfit and ran marathons 6 months ago. Please take it off the market.
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  • Oct 5th, 2013
    Someone from Killeen, TX writes:
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    I hate this shot! I've suffered from horrible mood swings...to thoughts of suicide. It makes me feel like I'm having out of body experiences...my thoughts are cloudy...and I feel like im going crazy...please take this drug off the market
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  • Oct 4th, 2013
    Someone from Oneonta, NY signed.
  • Oct 4th, 2013
    Someone from Oneonta, NY signed.
  • Oct 4th, 2013
    Someone from Palestine, TX writes:
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    I took Lupron as part of an IVF treatment. I was required to give myself injections daily in my stomach for 30 days. Since having my child (IVF worked on first attempt), I've experienced joint/bone pain in my hips, back, hands/fingers, feet. Not to mention my inability to sleep at night, irregular periods, hot flashes, inability to concentrate, stomach issues. I've been tested for RA, that came back negative. I have horrible pain during my monthly cycle that no medicine I've taken will touch. No endometriosis. I've just dealt with the pain and other issues. I've asked my fertility dr about these issues to which I'm told, "Nope, no one has ever complained of any of that after going through a round of IVF." I was floored at all the information I have recently found. When I first began experiencing these symptoms, I began doing research and couldn't find anything. I did more research last year and found a few things. Today, I've found a slew of different people who have used this drug for many different reasons. I must say this drug MUST NOT BE AVAILABLE anymore. I cannot imagine what I will feel like as I age. I am 31 and took this drug when I was 27. I'm still experiencing all of the issues I mentioned. They've never EVER gone away.
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  • Oct 4th, 2013
    Someone from Boise, ID writes:
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    My wife developed Psychosis... I had to check her in to a mental institute. Dealing with the side effects from this drug still. Please take this off the market!
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  • Oct 2nd, 2013
    Someone from Hamilton, OH writes:
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    I have been on long term Lupron use for about 3 years for treatment of my endometriosis and in that time have developed severe bone/joint pain, incapacitating body pain and fatigue, and memory loss. I have had countless bloodwork done, only to be told it is normal. I am currently seeing a rheumatologist who has diagnosed it all as fibromyalgia. My life has been forever changed since Lupron.
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  • Sep 30th, 2013
    Someone from Crown Point, IN writes:
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    Lots of symptoms even after Lupron is out of my system. It has changed my life!!!!!!
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  • Sep 29th, 2013
    Someone from Avon, CO writes:
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    I was diagnosed with prostate cancer May 2011. I ended up getting treatment at CTCA. I had many concerns and questions about Lupron, I was told that at the end of my three month shot I would have no side effect, Two years have pasted, I refused to continue treatment with Luprone. This page is not long enough to express my concerns and long term side effects that I have had sense taking only one three month shot. I am not the person I used to be, I have always been in great shape owned my own business for 30 years. fatigue and memory loss are just a few of the side effects that Have made life very difficult. I struggle daily to just get out of bed. Be Careful!!
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  • Sep 29th, 2013
    Someone from El Dorado, AR signed.
  • Sep 26th, 2013
    Someone from Southfield, MI signed.
  • Sep 25th, 2013
    Someone from Moreno Valley, CA signed.
  • Sep 25th, 2013
    Someone from Moreno Valley, CA signed.
  • Sep 23rd, 2013
    Someone from Glendale, AZ signed.
  • Sep 23rd, 2013
    Someone from Coxsackie, NY signed.
  • Sep 20th, 2013
    Someone from Kansas City, KS signed.
  • Sep 20th, 2013
    Someone from Pembroke, MA signed.
  • Sep 20th, 2013
    Someone from Oklahoma City, OK writes:
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    I had my first injection 3 weeks ago and have had severe adverse side effects since one hour after the injection, including one trip in an abulance on breathing machines and two ER visits for breathing treatments and four trips to my doctor for the long list of severe debilitating symptoms! Help us, this has to stop!
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  • Sep 20th, 2013
    Someone from Oklahoma City, OK writes:
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    I had my first injection 3 weeks ago and have had severe adverse side effects since one hour after the injection, including one trip in an abulance on breathing machines and two ER visits for breathing treatments and four trips to my doctor for the long list of severe debilitating symptoms! Help us, this has to stop!
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  • Sep 17th, 2013
    Someone from Purcellville, VA signed.
  • Sep 16th, 2013
    Someone from Albuquerque, NM writes:
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    I took the Lupron shot on December 2012. I took the second dose in March 2013. I have not had a period since November 2012 a month before I started the shot. I still have joint pain and still experience hot flashes. And while the on the shot I angry, depressed, I had night sweats, hot flashes, no sex drive. It was HELL!!!!!! And I feel like the Lupron shot made me worse then I was before I took the Lupron shot.
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  • Sep 15th, 2013
    Someone from Los Angeles, CA writes:
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    severe weight gain - skin fungus, extreme itching and bloody rashes.
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  • Sep 14th, 2013
    Someone from Easton, CT writes:
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    Horrible drug. Please get it off of the market before more people are harmed.
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  • Sep 14th, 2013
    Someone from Smyrna, DE writes:
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    I've had 2 shots. The 3 month dose and then the 1 month dose. I'm told by my doctor that the side effects should be gone by now but it's been 3 months since my last shot and the joint/bone pain is horrible. I've learned to live with the other side effects but the pain is too intense to bear. I'm 41 and had no joint pain prior to the shots but my doctors office is saying go see your family doctor to be tested, it could be a number of different things and the timing of the shot is coincidence. I take ibuprofen and naproxen everyday to try and find relief. I walk and do yoga stretches. Nothing helps. If I knew then what I know now, I would have said no and endured the endo pain a little longer until my hysterectomy could be done. But I trusted my doctor. I love my doctor. However, I think the side effects of this drug were overlooked and the wrong decision was made. Now I feel I'm being pushed aside to figure this out on my own. I'm scared and sad. Every day I wake up hoping this is the day I'll start to feel better and every day I get out of bed stiff, I walk down the stairs and get sharp pains in my knees, and I struggle to move through my day like a normal person. This drugs cons outweigh the pros by far.
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  • Sep 13th, 2013
    Someone from Unity, ME signed.
  • Sep 13th, 2013
    Someone from Oak Park, MI writes:
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    I received one shot of Lupron and I was told that it wears off in three months because I didn't take all three doses here I am one year later with terrible sweats through out the day and night and the side I received the injection on is in terrible pain a asked the Dr about the pain I was feeling was related to this shot and was told no know I know my bones are breaking down I only took this shot so I could stop bleeding long enough to have surgery had I known this medication was used for cancer I would have refused
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  • Sep 13th, 2013
    Someone from Oak Park, MI signed.
  • Sep 13th, 2013
    Someone from Oak Park, MI writes:
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    I received one shot of Lupron and I was told that it wears off in three months because I didn't take all three doses here I am one year later with terrible sweats through out the day and night and the side I received the injection on is in terrible pain a asked the Dr about the pain I was feeling was related to this shot and was told no know I know my bones are breaking down I only took this shot so I could stop bleeding long enough to have surgery had I known this medication was used for cancer I would have refused
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  • Sep 12th, 2013
    Someone from Beverly Hills, CA signed.
  • Sep 12th, 2013
    Someone from Long Beach, CA writes:
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    Very bad indeed even after all these years :--(
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  • Sep 12th, 2013
    Someone from Schenectady, NY signed.
  • Sep 11th, 2013
    Someone from Toms River, NJ signed.