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Investigation into Lupron Side Effects (Leuprolide Acetate)

Public Comments (5,065)
  • Sep 11th, 2013
    Someone from Noblesville, IN signed.
  • Sep 11th, 2013
    Someone from Muncie, IN signed.
  • Sep 9th, 2013
    Someone from Mason City, IA writes:
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    I was 7 years old wen I started my Lupron shot and I was 10 when they stopped giving it to me. I took it for starting puberty to early. I get my period once a year an I have a cyst on my left overy. I;m beginning to have memory loss and joint pain. I am now 21 yrs old and still suffering from the Lupron shot!
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  • Sep 6th, 2013
    Someone from Bartlett, IL writes:
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    Its been 15 years since I was on Lupron and still have problems with my memory
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  • Sep 6th, 2013
    Someone from Sarahsville, OH writes:
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    Since taking this shot I feel worest than the being problems I had. Thanks to my dr not telling all the horrible side effects.and after effects.
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  • Sep 4th, 2013
    Someone from Katy, TX signed.
  • Sep 2nd, 2013
    Someone from Chicago, IL writes:
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    I am still having issues with memory...brain farts, not being able to think of a word in the middle of a conversation.
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  • Sep 1st, 2013
    Someone from Mesa, AZ writes:
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    im am currently suffering horrible bone/joint/nerve pain from Lurpon. it started in my 3rd month of treatment and is still horribly painful 3 months after my last treatment. thank you for organizing this petition, just wish i knew about it before.
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  • Aug 30th, 2013
    Someone from Richmond, VA writes:
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    I took Lupron a few years ago - and became almost crippled for about a year. The bone/joint pain was non-stop and completely wore me out and broke me down. My life is still affected by all that happened as many doctors kept telling me- "these are not known side effects" and "we don;t know what's wrong with you." I was given NO pain management assistance.
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  • Aug 29th, 2013
    Someone from Raleigh, NC signed.
  • Aug 28th, 2013
    Someone from Tracy, CA signed.
  • Aug 28th, 2013
    Someone from Oklahoma City, OK signed.
  • Aug 26th, 2013
    Someone from Far Rockaway, NY writes:
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    have been on this shot because I was toll from my dr it was my only option.ive been in pain since and im on the shot now wont be taking another one.
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  • Aug 24th, 2013
    Someone from Philadelphia, PA writes:
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    I'm on my second shot of lupron 2 days ago I've started to experience servere leg an thigh pain an terrible back pain an shoulder pain I go for my 6 weeks visit will see what happens I had a total hysterectomy for endometries but my pain is worse just minus the bleeding my is over
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  • Aug 23rd, 2013
    Someone from Clovis, CA signed.
  • Aug 23rd, 2013
    Someone from Hampton, IL writes:
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    terrible joint pain from having it at high dose for breast ca, have to take pain pills daily to continue working. Reveived in 1998
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  • Aug 23rd, 2013
    Someone from Temecula, CA writes:
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    Stop giving out this drug or provide other alternatives for Medicare patients.
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  • Aug 23rd, 2013
    Someone from Memphis, TN signed.
  • Aug 22nd, 2013
    Someone from Tioga Center, NY writes:
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    I took Lupron injections back in 1999 for 6months and I am now 64 yrs.old and I have all these side effects and have had to retire early. I took Lupron under my Gynecologists strong encouraging words after doing a d@c. I had large Fybroids.Strangely enough my uterous grew in size after injections and I had a Hysterectomy and I am suffering the side effects from this horrible drug!!
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  • Aug 22nd, 2013
    Someone from Seattle, WA signed.
  • Aug 22nd, 2013
    Someone from La Vergne, TN signed.
  • Aug 21st, 2013
    Someone from Houston, TX signed.
  • Aug 21st, 2013
    Someone from Houston, TX writes:
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    My mother had Lupron treatments 20+ years ago, and has been suffering from problems similar to most others on this list ever since: severe joint pain, prevalent cysts, memory loss, restless legs, degenerative disc disease, low metabolic rate, etc.. I am abhorred by the lack of research into the long term effects of this drug - which clearly has horrific potential.
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  • Aug 21st, 2013
    Someone from Beverly Hills, FL writes:
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    I recieved lupron in 1998. I wish I never did. Like the others I had no previous health problems except endometriosis and fibroids. I suffered dailymigraines from the first shot which lasted a minimum of 10 years. Memory problems severe muscle pain and weakness. Infertility. Fibromyalgia. Heart failure. Legs swollen. Numbness tinging hans and face. Djd, osteoporosis. It awful I wish I never recieved lupron. I pray that stop giving this drug untill further long term studies are done.
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  • Aug 21st, 2013
    Someone from Beverly Hills, FL writes:
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    I recieved lupron in 1998. I wish I never did. Like the others I had no previous health problems except endometriosis and fibroids. I suffered dailymigraines from the first shot which lasted a minimum of 10 years. Memory problems severe muscle pain and weakness. Infertility. Fibromyalgia. Heart failure. Legs swollen. Numbness tinging hans and face. Djd, osteoporosis. It awful I wish I never recieved lupron. I pray that stop giving this drug untill further long term studies are done.
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  • Aug 21st, 2013
    Someone from Phoenix, AZ signed.
  • Aug 20th, 2013
    Someone from Overland Park, KS writes:
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    I took Lupron beginning in March of 2009, and experienced most of the common side effects, hot flashes, diminished sex drive, etc. and nine months later I had open heart surgery. I have read about the possible connection of Lupron with heart disease, and am concerned that the drug may have contributed to the exacerbation of my heart disease. My EKG has not been normal since before my open heart surgery. Every time I get an EKG they think I am having a heart attack! I have to convince them that this was the way it has been since before my surgery.
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  • Aug 20th, 2013
    Someone from Oakdale, CA writes:
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    Had a shot in 2009, now am going through ddd, osteoarthritis, tachycardia, immune issues, bone loss, and the list goes on. My sister warned me not to take the shot, so i told the dr. No. I dont want it. Found out a month later he gave it to me anyway when unexplained issues came up. Blisters on my skin that still come up when i get in the sun.!!! Stop!!! Dont take this drug. I found out 3 years later i didnt even have endo. Dr. Was completely incompetent.
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  • Aug 20th, 2013
    Someone from Fredericksburg, VA writes:
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    I was treated with Lupron for endo--something I suffered from for nearly two decades. Once relatively fit and certainly a go-getter, I have deteriorated to a shell of myself pre-lupron; the bone/joint/muscle pain is akin to being set on fire at times is the best way for me to describe it. There are morning, particularly when it is cold & damp, that it requires all that I am to get out of bed due to the pain being so severe. Only narcotics alleviate the pain. I am a mother of young children, so, such is rarely an option for me. My vision has deteriorated quite significantly, headaches that I never experienced before, fatigue that compares to that accompanied by a flu, and edema at times that makes my lower limbs feel as though they have been suddenly pumped full of water. Despite the "treatment" a hysterectomy was required. I would not wish what I go through as a result of the Lupron on my worst enemy.
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  • Aug 20th, 2013
    Someone from San Jose, CA writes:
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    This drug has destroyed my life. Doctors only tell you the side effects will bring you through menopause, they do not tell you all the other horrible stuff. Like you feel you are going crazy, joint pain, bad stomach pain, leg pain, not able to walk, depression, cramps, constipation, you name it I got it. It is now costing me a fortune going to alternative medicine doctors trying to get rid of the toxin's in my body. Please take this drug off the market and stop killing people!
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  • Aug 18th, 2013
    Someone from Monrovia, CA signed.
  • Aug 18th, 2013
    Someone from Deatsville, AL writes:
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    Lupron has destroyed both my physical and mental health. If I had only known that I would still be suffering the affects of this drug 20 years later, I would never have taken what my Doctor assured me was a safe drug. Guess he was wrong.
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  • Aug 17th, 2013
    Someone from Cape Coral, FL writes:
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    I was on Lupron in 2007, and my body went into a pregnancy state and my breasts filled with milk. I was taken off and had a hysterectomy in October 2007. I was only 27 years old, and had no children. Since that time, I have had degenerative disk in my neck, and had to have screws and plate put in my neck. Also have chronic migraines, and have had internal shingles three times, once shutting my bladder completely down. I have to use a catheter to go to the bathroom. It is now 2013 and I am still miserable and not able to work or get any type of aide....my life is a total disaster.
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  • Aug 17th, 2013
    Someone from Hollywood, FL writes:
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    I took Lupron for endometrosis for about 9 months and didn't have any immediate side effects except hot flashes, however, 15 years later I have severe joint pain everywhere. I'm way too young for this.
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  • Aug 17th, 2013
    Someone from Garden City, MI signed.
  • Aug 17th, 2013
    Someone from Garden City, MI signed.
  • Aug 16th, 2013
    Someone from Brighton, MI writes:
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    I am a two time breast cancer patient and survivor given lupron depot injections to halt estrogen production, as my cancer was ER positive. Horrible and numerous side effects included but were not limited to: debilitating bone, muscle and nerve related pain, neuropathy in hands, memory loss, anxiety and insomnia. I stopped taking the drug after 1 year into a five year course of treatment and opted for a total hysterectomy and removal of my ovaries. It has been months since my last injection and debilitating side effects have persisted. This drug is awful....bottom line. FYI... I am NOT a complainer or a whiny blogger. I would like to make that clear. I also have a deep appreciation for the Docs and the medications and treatments that have twice saved my life. Lupron is NOT one of them.
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  • Aug 16th, 2013
    Someone from Brighton, MI writes:
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    2 time breast cancer patient given lupron depot injections to halt estrogen production as cancer was ER positive. horrible and numerous side effects included but were not limited to: debilitating bone, muscle and nerve related pain, neuropathy in hands, memory loss, anxiety and insomnia. i stopped taking the drug after 1 year in a five course year of treatment and opted for a total hysterectomy and removal of my ovaries... it has been months since my last injection and side effects have persisted. this drug is awful....bottom line. FYI... i am NOT a complainer or whiny blogger.
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  • Aug 15th, 2013
    Someone from Los Angeles, CA signed.
  • Aug 14th, 2013
    Someone from Loveland, CO signed.