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Investigation into Lupron Side Effects (Leuprolide Acetate)

Messages Sent So Far
The purpose of this petition is to warn others regarding the drug Lupron (Leupolide Acetate) mfg. by Takeda/Abbott Pharmaceuticals in the hope that further long-term safety studies are done before it disables or kills more women. This drug was originally marketed to treat prostate cancer patients but now is widely used for the treatment of endometriosis, infertility, fibroids/ovarian cysts and even precocious puberty.

Many women are continuing to suffer the side effects long after taking their last dose even though their doctor and the pharmaceutical company states that the side effects should go away within 3-6 months. Side effects include but are not limited to: hot flashes, memory loss, tachycardia, hematura, hypotension, dizziness, insomnia, anxiety, depression, Vitamin D deficiency, constant gnawing bone/joint pain, osteoarthritis, osteopenia, osteoporosis, fibromyalgia, degenerative disc disease, autoimmune diseases, blood disorders, cancer and many others including death and yet not one long term study has been conducted.

It is devastating to us that we agreed to take an FDA approved drug under the care of our physician whom we trusted only to find ourselves sicker than you could imagine ---- in pain and unable to get the proper treatment or even believed that Lupron caused our problems.

We hereby request that an investigation be undertaken into the short term and long term effects of Lupron on women. We further request that all outcomes and results of such trials be released and published so that both patients and doctors alike may have the benefit of all the information regarding this drug.

Public Comments
Jan 11th, 2018
Someone from Chattanooga, TN writes:
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My daughter was prescribed Lupron for CPP in 2014 and has received monthly injections for almost 4 years. I have been repeatedly assured that there would be no long term side effects. I am just now realizing the risk I have taken with my child's health. Had I have known even the limited information I know now about Lupron, I never would have given it to my daughter. It's too late for my family, but further research is desperately needed on this drug and it's long term effects on children.
Jan 11th, 2018
Someone from Chattanooga, TN signed.
Jan 10th, 2018
Teddi Y. from Winterset, IA writes:
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This drug has ruined my sister’s life and I know she doesn’t want a single other person to go through what she has.
Jan 10th, 2018
Holly J. from Bothell, WA writes:
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Since my last injection of Lupron Depot in May of 2014, I have gone from being a very healthy and active woman to nearly disabled. I have been diagnosed with FIBROMYALGIA, Cyclic vomiting syndrome, hypermobility of the joints, Arthritis, Unexplained abdominal pain, breaking teeth, several strains, fractures, 60 pound weight gain, constant sweating, heart palpitations, memory loss, and feeling like I have the flu every single day of my life. I know I am just one of thousands of sufferers. TAP Pharmaceuticals needs to be held accountable for the thousands of lives they have ruined.
Jan 8th, 2018
Mary E. from South Houston, TX signed.
Jan 8th, 2018
Mary E. from South Houston, TX signed.
Jan 8th, 2018
Mary E. from South Houston, TX signed.
Jan 6th, 2018
Someone from Boca Raton, FL writes:
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I did this search to find out about Lupron after reading that is now given to transgender children to prevent “puberty” since I was given for fibroids. WOW having had taken this drug back in 1990 I too now wonder what I thought was “old age” (60) is the result of this drug, that was almost 30 years ago and seeing all these other post I cant believe i’ve Never been asked about it, It sounds like we need to stop giving this to children and find a safer option.
Jan 5th, 2018
Joni M. from Dublin, OH writes:
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I was given Lupron injections for several months in 2008 as treatment for pelvic pain. I was diagnosed 2017 with multiple myeloma, impaired immune function and severe osteoporosis, bone pain. It never did help my symptoms of pelvic pain. There must be a connection.
Jan 5th, 2018
Joni M. from Dublin, OH writes:
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I was given Lupron injections for several months in 2008 as treatment for pelvic pain. I was diagnosed 2017 with multiple myeloma, impaired immune function and severe osteoporosis, bone pain. It never did help my symptoms of pelvic pain. There must be a connection.
Jan 2nd, 2018
Amy G. from Duluth, GA signed.
Dec 16th, 2017
Alesia W. from Salt Lake City, UT signed.
Dec 14th, 2017
Someone from Mackinaw, IL writes:
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I started taking lupron in 2010 due to endometriosis and was told it would help me have a baby. I immediately became so depressed I was put on antidepressants and I've been on them ever since. I since have gained weight until I was over 200lbs, had relationship issues related to depression, quit a job from my depression that I worked at for almost 9 years. I was always average to skinny before. I have to take phentermine just to not gain weight. I've had testing done on cholesterol levels and my thyroid. My thyroid levels are low end of the normal range, My blood sugar was elevated and cholesterol was higher than average. I have a difficult time with short term memory, where my brain becomes so fogged, it takes me forever to remember what I was thinking just a minute ago. I recently started having very sharp pains in my joints, I have been to physical therapy for a Nerve problem in my back that has never fully went away, I have really bad legs cramping all the time, severe depression, severe headaches (I take tylenol daily), decreased hemoglobin levels, hot flashes have happened a couple times, I have been to ER for dizziness, I am ALWAYS tired, and am concerned it may have affected my bone density. This product SHOULD NOT be on the market. I have taken 3-4 injections shots given at my Dr office beginning in 2010. They were the 3 month shots and roughly lasted 5 months.
Dec 7th, 2017
Kimberly R. from Delray Beach, FL writes:
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My son was given Lupron at 11 years old for precocious puberty! He started complaining of leg cramping about every other month. He then would develop a fever for about a week at a time every other month. He got Bell's palsy, and his moods were off the charts. The endocrinologist insisted it was NOT from the Lupron. After 6 months I took him off of it and he no longer got sick. Now he is 20, and suffers from anxiety, depression, and muscle aches. He did not have any of this before the Lupron.
Nov 27th, 2017
Amanda M. from Corning, IA writes:
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I feel like I’ve been fighting for my life ever since I took this drug,3 injections total, for uterine fibroids. Thyroid problems, body pain & fatigue Overall unhealthy state of physical being
Nov 23rd, 2017
Olga M. from Morrisville, NC writes:
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This drug is poison with horrible side effects. I barely can walk due to excruciating pain in my feet caused by only 1 Lupron ejection. Headache, nausea, ache and body pain, stomach issues, weight gain, the list goes on. Kill Lupron because Lupron kills!
Nov 15th, 2017
Sarah M. from Perrysville, IN signed.
Nov 4th, 2017
Kasia C. from Petaluma, CA writes:
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This "medicine" is pure poison! It has left me and my Father with permanent side effects!! Not to mention, this medicine does NOT stop progression or Endo, it doesn't shrink Endo lesions, it does not eradicate the disease in any way shape or form! While some may experience relief in Peritoneal Quality Pain, it is a band-aid at best! It's time to stop perpetuating the false, 100 year old theory regarding Endo! The treatment with the highest success rate is Expert Excision!!!
Nov 3rd, 2017
Cindy Y. from Forked River, NJ writes:
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This drug is absolute POISON!! How it is still on the market just shows how corrupt the FDA and our government is! This drug has ruined my life! Shame on all of those who are allowing this to continue to destroy lives!
Nov 2nd, 2017
Someone from Oswego, NY writes:
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Lupron for endometriosis is the stuff of nightmares, on so many levels. It is unjust to do this to women. We need those in authority to speak up.
Oct 31st, 2017
Salley A. from Oxford, MS writes:
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Please take action.
Oct 24th, 2017
Someone from Erie, MI writes:
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How is this drug not being pulled it’s ruined so many lives!
Oct 20th, 2017
Allison D. from Saint Charles, MO signed.
Oct 14th, 2017
Kristen c. from Jeffersonville, IN writes:
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This drug has distroyed my life.
Oct 14th, 2017
Kimberly J. from Henderson, NV writes:
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In my opinion this drug damaged my life permanently.
Oct 13th, 2017
Someone from Twin Lake, MI writes:
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I received only 3 injections and I stopped. It was over 15 years ago but I am curious if there are side effects from it that are starting to occur even now. My complexion has always been good and I have a lot of facial hair and spots that are awful.. I never had any facial hair until I began the Lupron. Just curious if there are any other women who have similar symptoms
Oct 11th, 2017
Amie H. from Martin, TN writes:
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Since my six injections of Lupron life has not been the same pain getting to the point can’t handle vit D def. low thyroid gallbladder removed keep blood in my urine
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 9th, 2017
Barbara B. from Ford city, PA writes:
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I don't understand why justice has not been served yet . Each day, i see several commercials re: several different drugs. It is usually a law firm or spokesperson, stating, if you've had these side effects call these attornies. These drugs are relatively new , & havent been on the market long. Lupron has caused equally devastating comsequences , sometimes much worse and has continued to do so for decades. I realize lupron brings in almost a billion dollars a year. Tell me who is responsible for preventing justice.
Oct 5th, 2017
Kristen c. from Jeffersonville, IN signed.
Sep 26th, 2017
Joann D. from Worth, IL writes:
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Lupron had ruined my health. Please do not allow this drug to do the same to anyone else.
Sep 24th, 2017
Cheryl H. from Palm Harbor, FL writes:
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In 2008, I was prescribed Lupron. I took it for only two days before having memory problems so severe I was not able to speak. Upon stopping, I was a little better but I continue today to struggle with memory and pituitary issues. I can trace my problems to the exact point. It was not a gradual onset. It was immediate and thusfar, permanent. I was not counseled about the severity of this drug. I was given this drug by a military doctor, and expected to follow orders.
Sep 21st, 2017
Someone from Nacogdoches, TX writes:
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Lupron is a poison. My doctor never talked to me about long term side effects. She always said once we discontinue the injections your body will go back as it should be. Today, 4 years later I am 28 years old and feel I can't go on living like this. I have constant bone and joint pain, insomnia, anxiety, depression, hypertension, and have had tendencies of suicide. I have had no period in years and I am becoming worse as time goes on. I am in so much pain and I am scared of my future. I am not able to have a routine job. I fear I will be bed ridden. It is a terrible, terrible drug that causes painful side effects physically, mentally and emotionally. These drug companies should be sued and forced to take this drug off the market.
Sep 16th, 2017
Kelsey S. from Paradise, CA writes:
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How many requests must be received in order for an investigation?
Sep 15th, 2017
Timothy L. from Holly, MI signed.

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